Examination of the left eye revealed ulcers and necrotic tissue involving the upper and lower eyelid, erythema, slight periorbital edema, and induration. The thickness of the left upper eyelid near the medial canthus was completely lost. The only visible part of the left eye was a small part of the sclera and bulbar conjunctiva. The orbital wall could not be identified because of numerous live white and shiny larvae crawling over the fleshy mass (Fig. 1). We manually removed 50 larvae from the left eye and nostril with forceps. Furthermore, debridement of the necrotic tissue was performed in an emergency room under topical anesthesia (pantocaine 2% eye drops). We diagnosed the patient as having massive orbital myiasis. The larvae were stored in a saline solution for further investigation (Fig. 2). All the larvae could not be removed in a single sitting as they kept invading the remaining ocular tissue and nasal cavity. Computed tomography of the sinus paranasal of the coronal section showed pansinusitis, visible cloaking, shadow abscess, and presumed insects filling the left maxillary and ethmoidal sinuses and nasal cavity and reaching the left orbital cavity accompanied with bone destruction (left maxillary and ethmoidal sinuses wall) and nasal septum destruction (Fig. 3). Chest X-ray revealed right pleuropneumonia. The patient was hospitalized for further treatment and co-treated by the Ear, Nose, and Throat and Internal Medicine Department. The larvae were identified as Chrysomya bezziana (Fig. 4). Complete larvae removal from nasal and orbital cavities was done through nasal endoscopy. Intravenous antibiotic (ceftriaxone 1 gr/12 h), chloramphenicol eye ointment, and nasal decongestant drops improved the patient symptoms, and insulin glulisine 12-12-12 helped the patient control the blood sugar level. The patient was discharged from the inpatient ward after a successful removal of the larvae (see Fig. 5).